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Otto S, et al., Custom-milled individual allogeneic bone grafts for alveolar cleft osteoplasty - A technical note, Journal of Cranio-Maxillo-Facial Surgery (2017),Volume 45, Issue 12, December 2017, Pages 1955-1961 https://doi.org/10.1016/j.jcms.2017.09.011 Surgeons from the Ludwig-Maximilians-University in Munich, Germany, showcase in this technical note the successful repair of an alveolar cleft using maxgraft® bonebuilder, an individualized allogeneic bone graft, in a 36-year old female patient with a 6-month-follow up showing good bony integration.   Cleft lip and palate is among the most frequent congenital abnormalities around the world. Of all cases, 75% are associated with osseous defects of the alveolus. Bone grafting of the alveolar cleft is often indispensable to allow a descent of the canine adjacent to the cleft or an orthodontic closure of the tooth row. The patient with a cleft alveolus with a continuous bony gap reaching from the alveolar crest (in region 22) into the piriform rim and nasal floor chose an...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Soft tissue augmentation with mucoderm® On the occasion of the annual meeting of the German Society of Implantology (DGI) in Hamburg on November 26, 2016, seven leading experts with both a strong scientific and clinical background in the field of dental soft tissue reconstruction met to review the current status of peri-implant and periodontal soft tissue management. The discussion focused particularly on the clinical application and experience with the collagen matrix called mucoderm®, published data and data in preparation, as well as the potential limitations of its use, including in comparison with autologous soft tissue grafts.     [/vc_column_text][/vc_column][vc_column width="1/3"][vc_column_text]Read this article also on [/vc_column_text][/vc_column][/vc_row][vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] mucoderm® - an acellular dermal matrix designed for soft tissue reconstruction mucoderm® is a natural type I/III collagen matrix derived from porcine dermis that undergoes a multi-stage purification process to remove all non-collagenous proteins and cells,...

Médecins Sans Frontières provides assistance to populations in distress, to victims of natural or man-made disasters and to victims of armed conflict. The international organization aids fast, efficient and unbureaucratically – irrespective of race, religion, creed or political convictions of the people affected. Further information: http://www.msf.org...

The comprehensive study of the group of Prof. Kasaj confirms that mucoderm can be used as a carrier of bioactive fluids (Emdogain® and PRF®) to improve the clinical outcome. Coating of the porcine collagen matrix mucoderm® with Emdogain® and PRF-resulted in improved cell behavior (cell attachment, proliferation, migration) of human umbilical vein endothelial cells in vitro. Therefore, the application of bioactive fluids to mucoderm® could be useful with regard to the clinical outcome and healing process in periodontal plastic surgery and implantology. Biofunctionalization of porcine-derived collagen matrix using enamel matrix derivative and platelet-rich fibrin: influence on mature endothelial cell characteristics in vitro. Park et al. 2017; Clin Oral Investig. doi: 10.1007/s00784-017-2170-7. https://www.ncbi.nlm.nih.gov/pubmed/28695450  ...

With the introduction of permamem®, botiss expands its regeneration system by offering an exceptionally thin, non-resorbable, biologically inert and biocompatible membrane made of 100% high-density polytetrafluoroethylene (PTFE). permamem® maintains its structural integrity during implantation and over time. Due to its small pore size the membrane acts as an efficient barrier against bacterial and cellular penetration, and may therefore be left in place for open healing in certain clinical indications. permamem® can easily be removed after the desired healing time with a pair of tweezers. After removal, the primary healing process and the reepithelialization of the regenerating soft tissue will be completed within one month. permamem® fulfills the requirements of biocompatibility according to EN ISO 10993-1 and EN ISO 7405. The biocompatibility of the membrane has been proven by in vivo preclinical data [1]. > MORE ABOUT PERMAMEM® [1] Barbeck M. et al. unpublished...

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Dear Customers, During the Christmas holidays (24.12.2016 to 01.01.2017) our office is only partly occupied. We will process your requests on January 2nd. Thank you very much for your understanding. Your botiss biomaterials Team [/vc_column_text][/vc_column][/vc_row]...

A new study about a novel liquid carrier system for enamel matrix proteins in combination with collacone® has recently been published: Miron RJ, Fujioka-Kobayashi M, Zhang Y, Sculean A, Pippenger B, Shirakata Y, Kandalam U, Hernandez M. Osteogain® loaded onto an absorbable collagen sponge induces attachment and osteoblast differentiation of ST2 cells in vitro. Clin Oral Investig. 2016 Dec 1. [Epub ahead of print] https://www.ncbi.nlm.nih.gov/pubmed/27909893 Objectives: The goal of this study was to determine the potential of Osteogain®, a liquid carrier for enamel matrix derivative, in combination with collacone® as a regenerative therapy for extraction socket management. The collacone® sponge was loaded with Osteogain® and the protein resorption and release as well as osteoblast binding and differentiation were investigated. Results: The proteins in Osteogain® were efficiently absorbed by collacone® and gradually released after a 10-day time period. Osteogain® induced a 50% increase in cell adhesion to collacone® and significantly stimulated cell differentiation as evidenced by the...

Parallel to the DGI annual meeting, the second expert meeting on mucoderm® will take place in Hamburg on 25.11. The group of international renowned clinicians will discuss recent study results, the current state of scientific evidence as well as surgical procedures and protocols for the following indications: recession coverage, augmentation of the attached gingiva and soft tissue thickening. We are looking forward to the stimulating exchange of scientific/clinical knowledge and the resulting outcome.  ...

[vc_row row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css_animation=""][vc_column][vc_column_text] Guided tissue and guided bone regeneration (GTR, GBR) are well-established techniques in dentistry to augment lost tissue around teeth and dental implants respectively (Nyman et al. 1980, Karing et al. 1980, Nyman et al. 1982, Dahlin et al. 1988). The basic principle of these methods is the placement of a barrier membrane between the soft tissue and residual bone in order to prevent the fast-proliferating epithelial cells from populating the bony defect and to provide space and time for the migration of slow-dividing osteogenic or periodontal ligament cells into the defect area.   Dr. Sascha Böhm and Dr. Sandra Wrobel, Scientific Product Managers at botiss biomaterials, Berlin/Germany. In the course of the evolution of GTR and GBR techniques, different types of membranes have been developed. Today, commercially available barrier membranes for GTR or GBR procedures can be divided into either non-resorbable or resorbable membranes. Non-resorbable membranes,...

Watch the Interview about the bone & tissue days Berlin 2016 with botiss' Director International Sales & Marketing, Zoltan Kasap, at the EAO Congress in Paris.   5dentalminutes.com...