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Zafiropoulos et al. Changes of the peri‑implant soft tissue thickness after grafting with a collagen matrix. J Indian Soc Periodontol. 2016 Jul-Aug;20(4):441-445. https://www.ncbi.nlm.nih.gov/pubmed/28298828 Study aim and design: The study determined the treatment outcome of the use of mucoderm® to increase soft tissue volume as a part of implant site development. 27 patients were randomly assigned to one of two groups: mucoderm® (test) versus no biomaterial (control). The soft tissue thickness was measured at two different points at surgery and after 6 months. Results: The results showed a significant increase of the soft tissue thickness (STTh 1 = 1.06 mm, 117%; STTh 2 = 0.89 mm, 81%) in the test group. Biopsy results showed angiogenesis and mature connective tissue covered by keratinized epithelium. It was concluded that mucoderm® leads to a significant increase of peri-implant soft-tissue thickness, with good histological integration and replacement by soft tissue and may serve as an alternative to connective tissue grafting....

Vincent-Bugnas et al. Treatment of multiple maxillary adjacent class I and II gingival recessions with modified coronally advanced tunnel and a new xenogeneic acellular dermal matrix. J Esthet Restor Dent. 2017 Sep 13. https://www.ncbi.nlm.nih.gov/pubmed/28901687 Study aim and design: The study aimed to evaluate the treatment of maxillary Miller Class I and II multiple adjacent gingival recessions using the modified coronally advanced tunnel technique (MCAT) combined with muocderm®. 12 patients exhibiting at least 6 adjacent recessions were treated. Results: At 12 months, complete root coverage was obtained in 43% of the 100 gingival recessions, while the mean root coverage measured 84.35%. All patients were satisfied with the aesthetic appearance and would undergo the same surgery again. The authors concluded that treatment of Miller Class I and II multiple gingival recessions using mucoderm® in conjunction with the MCAT could be successfully used as an alternative to connective tissue grafts, with the advantage of avoiding the discomfort and morbidity of...

Fujioka-Kobayashi et al. In vitro evaluation of an injectable biphasic calcium phosphate (BCP) carrier system combined with recombinant human bone morphogenetic protein (rhBMP)-9. Bio-Medical Materials and Engineering 28 (2017) 293–304. https://www.ncbi.nlm.nih.gov/pubmed/28527192 Study aim and design: The study evaluated the possibility of combining maxresorb® inject with growth factors by analyzing adsorption of rhBMP9 as well as adhesion, proliferation, viability and differentiation of stromal cells. Results: The results demonstrated that maxresorb inject serves as an excellent carrier for the growthfactors. The bone paste showed very good adsorption/retention potential of rhBMP9 with a slow and steady release over a 10 day period. The combination of maxresorb® inject and rhBMP9 demonstrated a good osteoinductive potential by positively influencing the osteoblastic differentiation of stromal cells....

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css=".vc_custom_1513510348027{margin-right: 20px !important;margin-left: 20px !important;}"][vc_column][vc_column_text css=".vc_custom_1513511719795{margin-bottom: 60px !important;}"]To commemorate the receipt of the CE marking certification of cerabone® 15 years ago, five leading experts, with extensive experience in the field of dental bone regeneration and a solid clinical experience with cerabone®, gathered to discuss all relevant aspects of the clinical performance of the bone grafting material. The debate predominantly focused on the clinical indications of cerabone® and its handling. The goal of the meeting was to develop an indication-based guideline for the clinical use of cerabone®, i.e. which basic principles should be followed when using cerabone® for different bone augmentation procedures. Experts invited were Assoc. Prof. Dr. Ziv Mazor (Raanana, Israel), Dr. Alessandro Rossi (University of Milan, Italy), Dr. Pedro Lázaro Calvo (Madrid, Spain), PD Dr. mult. Peer Kämmerer (University Medical Centre Rostock, Germany) and Dr. Marko Blašković (Rijeka, Croatia).[/vc_column_text][vc_separator type="normal" color="#999999" up="20px"][vc_accordion active_tab="false"...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text] Healing of localized gingival recessions treated with a coronally advanced flap alone or combined with an enamel matrix derivative and a porcine acellular dermal matrix: a preclinical study. Shirakata et al. Clin Oral Investig. 2016 Sep;20(7):1791-800. https://www.ncbi.nlm.nih.gov/pubmed/26612398 Principal finding: The combined use of mucoderm® and Emdogain® in coronally advanced flap procedures may promote periodontal regeneration in gingival recession defects. [/vc_column_text][/vc_column][/vc_row][vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" padding_top="20px" padding_bottom="20px"][vc_column][vc_separator type="normal" color="#00ccff"][/vc_column][/vc_row][vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text] Collagen Membranes Adsorb the Transforming Growth Factor-β Receptor I Kinase-Dependent Activity of Enamel Matrix Derivative. Stähli et al. J Periodontol. 2016 May;87(5):583-90. https://www.ncbi.nlm.nih.gov/pubmed/?term=st%C3%A4hli+collagen+membranes Principal finding: mucoderm® has the ability to adsorb the TGF-β activity intrinsic to Emdogain® and makes it available for oral fibroblasts.[/vc_column_text][/vc_column][/vc_row][vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" padding_top="20px" padding_bottom="20px"][vc_column][vc_separator type="normal" color="#00ccff"][/vc_column][/vc_row][vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column][vc_column_text] Biofunctionalization of porcine-derived collagen matrix using enamel matrix derivative and platelet-rich fibrin:...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern" css=".vc_custom_1509384895058{padding-right: 50px !important;padding-left: 50px !important;}"][vc_column][vc_column_text]This case report describes the predictable coverage of multiple adjacent maxillary gingival recessions using the modified coronally advanced flap (MCAF) technique and modified coronally advanced tunnel technique (MCAT) in conjunction with an acellular porcine-derived collagen matrix (mucoderm®) combined with enamel matrix derivative (Straumann® Emdogain®). The author states: "In my opinion, this case can be viewed as satisfactory both for the patient and the operator, effectively demonstrating the benefits of the combination of mucoderm® and Emdogain® as regards time and pain."[/vc_column_text][vc_column_text] Initial situation A 30-year old female patient in good general health conditions presented with Miller Class I gingival recessions in the upper jaw affecting the teeth #12, #13 and #14 and teeth #22, #23 and #24 (Figs. 1-3), and was referred to our office by an orthodontist colleague (Enikő Szívos, DMD, orthodontist). The patient sought a minimally invasive approach to...

Chirurgen der LMU München zeigen in diesem Fallbericht die erfolgreiche Durchführung einer tertiären Kieferspaltosteoplastik unter Anwendung von maxgraft® bonebuilder bei einer 36-jährigen Patientin mit guter Knochenintegration nach sechs Monaten.   Otto S, et al., Custom-milled individual allogeneic bone grafts for alveolar cleft osteoplasty - A technical note, Journal of Cranio-Maxillo-Facial Surgery (2017), Volume 45, Issue 12, December 2017, Pages 1955-1961 https://doi.org/10.1016/j.jcms.2017.09.011   Cleft lip and palate is among the most frequent congenital abnormalities around the world. Of all cases, 75% are associated with osseous defects of the alveolus. Bone grafting of the alveolar cleft is often indispensable to allow a descent of the canine adjacent to the cleft or an orthodontic closure of the tooth row. The patient with a cleft alveolus with a continuous bony gap reaching from the alveolar crest (in region 22) into the piriform rim and nasal floor chose an allogeneic bone graft over iliac crest grafting for her tertiary...

[vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] Soft tissue augmentation with mucoderm® On the occasion of the annual meeting of the German Society of Implantology (DGI) in Hamburg on November 26, 2016, seven leading experts with both a strong scientific and clinical background in the field of dental soft tissue reconstruction met to review the current status of peri-implant and periodontal soft tissue management. The discussion focused particularly on the clinical application and experience with the collagen matrix called mucoderm®, published data and data in preparation, as well as the potential limitations of its use, including in comparison with autologous soft tissue grafts.     [/vc_column_text][/vc_column][vc_column width="1/3"][vc_column_text]Read this article also on [/vc_column_text][/vc_column][/vc_row][vc_row css_animation="" row_type="row" use_row_as_full_screen_section="no" type="full_width" angled_section="no" text_align="left" background_image_as_pattern="without_pattern"][vc_column width="2/3"][vc_column_text] mucoderm® - an acellular dermal matrix designed for soft tissue reconstruction mucoderm® is a natural type I/III collagen matrix derived from porcine dermis that undergoes a multi-stage purification process to remove all non-collagenous proteins and cells,...

Eine vergleichende Studie aus der Arbeitsgruppe von Prof. Kasaj bestätigte, dass mucoderm® als Träger von bioaktiven Substanzen (Emdogain® und PRF®) eingesetzt werden kann, um das klinische Ergebnis zu verbessern. Das Beladen der porcinen Kollagenmatrix mucoderm® mit Emdogain oder PRF zeigte in vitro ein verändertes Zellverhalten (bessere Zellhaftung, Proliferation, Migration) von humanen Nabenschnur-Entdothelzellen.  Die Verwendung der bioaktiven Substanzen mit mucoderm® könnte sich somit positiv auf das klinische Ergebnis und den Heilungsprozess in der Parodontalchirurgie und Implantologie auswirken. Biofunctionalization of porcine-derived collagen matrix using enamel matrix derivative and platelet-rich fibrin: influence on mature endothelial cell characteristics in vitro. Park et al. 2017; Clin Oral Investig. doi: 10.1007/s00784-017-2170-7. https://www.ncbi.nlm.nih.gov/pubmed/28695450  ...

Im vergangenen Jahr wurden mehr als 20 wissenschaftliche Artikel mit botiss Produkten zur Knochen- und Weichgeweberegeneration veröffentlicht. Zu den kürzlicht veröffentlichten Artikeln gehören: - NEUE STUDIE zu cerabone® - NEUE STUDIE zu maxresorb® Sehen Sie sich auch unsere Sammlung der wissenschaftlichen Artikel auf botiss-dental.com und botiss.com an....