{"id":11908,"date":"2018-12-03T09:14:40","date_gmt":"2018-12-03T08:14:40","guid":{"rendered":"https:\/\/botiss.com\/product\/gingiva-thickening-with-a-porcine-collagen-matrix-in-a-preclinical-dog-model-histological-outcomes-2\/"},"modified":"2024-07-24T10:00:12","modified_gmt":"2024-07-24T08:00:12","slug":"gingiva-thickening-with-a-porcine-collagen-matrix-in-a-preclinical-dog-model-histological-outcomes-2","status":"publish","type":"product","link":"https:\/\/botiss.com\/es\/producto\/gingiva-thickening-with-a-porcine-collagen-matrix-in-a-preclinical-dog-model-histological-outcomes-2\/","title":{"rendered":"Gingiva thickening with a porcine collagen matrix in a preclinical dog model: histological outcomes."},"content":{"rendered":"<p><span style=\"color: #00ccff;\"><strong>Schmitt CM et al. 2019. J Clin. Periodontol. 46(12):1273-1281<\/strong><\/span><\/p>\n<p><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31517397\" target=\"_blank\" rel=\"noopener noreferrer\"><strong><span style=\"color: #000000;\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31517397<\/span><\/strong><\/a><\/p>\n<p><strong>The preclinical study presented a slightly better outcome on soft tissue thickening for the gold standard, the subepithelial connective tissue graft (SCTG) but no differences were detected in terms of tissue quality at 10 months. Both grafted tissues, showed mature connective tissue, rich in blood vessels and cells and comparable collagen I and VEGF expression pattern.<\/strong><\/p>\n<p><span style=\"color: #00ccff;\">Aim:<\/span> Investigation of the histological and immunohistological outcomes of soft tissue thickening with mucoderm\u00ae and SCTG at 10 months follow-up.<\/p>\n<p><span style=\"color: #00ccff;\">Material\/Methods:<\/span> Eight beagle dogs received buccal soft tissue thickening of the left or right upper canine by inserting mucoderm\u00ae or SCTG, respectively in a split-mouth design. At 10 months, tissue thickness was histomorphometrically measured and tissues were harvested for histological and immunohistological analyses.<\/p>\n<p><span style=\"color: #00ccff;\">Results:<\/span> Connective tissue thickness differed significantly between mucoderm\u00ae (1.06mm) and SCTG (1.32mm) at 10 months, but no differences were found for tissue quality &#8211;\u00a0 such as anatomical structures. Both tissue grafts resulted in mature connective tissue in the augmented region, which were rich in blood vessels and cells. Furthermore, both grafted tissues were bound to the periosteum showing mature collagen fibers. Also the collagen I and VEGF expression did not differ between the groups and showed no inflammatory response.<\/p>\n<p><span style=\"color: #00ccff;\">Conclusion:<\/span> Although soft tissue thickening with the SCTG was superior to mucoderm\u00ae at 10 months, both tissue grafts presented very good results for soft tissue augmentation procedures with comparable tissue quality.<\/p>\n<p><span style=\"color: #00ccff;\">Christian M. Schmitt<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Schmitt CM et al. 2019. J Clin. Periodontol. 46(12):1273-1281 https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31517397 The preclinical study presented a slightly better outcome on soft tissue thickening for the gold standard, the subepithelial connective tissue  &#8230;<\/p>\n","protected":false},"featured_media":11755,"template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"product_brand":[],"product_cat":[2063,2059],"product_tag":[1952,1935],"class_list":["post-11908","product","type-product","status-publish","has-post-thumbnail","product_cat-scienza","product_cat-studi","product_tag-mucoderm-it","product_tag-gestione-dei-tessuti-molli","first","instock","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Gingiva thickening with a porcine collagen matrix in a preclinical dog model: histological outcomes. - botiss biomaterials GmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/botiss.com\/es\/producto\/gingiva-thickening-with-a-porcine-collagen-matrix-in-a-preclinical-dog-model-histological-outcomes-2\/\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Gingiva thickening with a porcine collagen matrix in a preclinical dog model: histological outcomes.\" \/>\n<meta property=\"og:description\" content=\"Schmitt CM et al. 2019. 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