{"id":72865,"date":"2026-09-22T14:52:16","date_gmt":"2026-09-22T12:52:16","guid":{"rendered":"https:\/\/botiss.com\/?post_type=product&#038;p=72865"},"modified":"2026-09-30T10:34:35","modified_gmt":"2026-09-30T08:34:35","slug":"atomic-force-microscopy-characterization-of-a-three-dimensional-porcine-collagen-matrix-for-periodontal-applications-under-hydrated-conditions","status":"publish","type":"product","link":"https:\/\/botiss.com\/fr\/produit\/atomic-force-microscopy-characterization-of-a-three-dimensional-porcine-collagen-matrix-for-periodontal-applications-under-hydrated-conditions\/","title":{"rendered":"Atomic Force Microscopy Characterization of a Three-Dimensional Porcine Collagen Matrix for Periodontal Applications Under Hydrated Conditions"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1200px;margin-left: calc(-0% \/ 2 );margin-right: calc(-0% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:0%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0%;--awb-width-medium:100%;--awb-spacing-right-medium:0%;--awb-spacing-left-medium:0%;--awb-width-small:100%;--awb-spacing-right-small:0%;--awb-spacing-left-small:0%;\"><div class=\"fusion-column-wrapper fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1\"><p data-prosemirror-content-type=\"node\" data-prosemirror-node-name=\"paragraph\" data-prosemirror-node-block=\"true\" data-pm-slice=\"1 1 &#091;&#093;\"><em><strong>Modern Science Journal (2026). \u2028 <a href=\"https:\/\/doi.org\/10.22551\/MSJ.2026.02.20\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.22551\/MSJ.2026.02.20<\/a><\/strong><\/em><\/p>\n<p>In this exploratory study atomic force microscopy (AFM) was used to characterize the nanoscale surface topography of the three-dimensional porcine collagen matrix (<a href=\"https:\/\/botiss.com\/product\/mucoderm\/\" target=\"_blank\" rel=\"noopener\"><strong data-prosemirror-content-type=\"mark\" data-prosemirror-mark-name=\"strong\">mucoderm<sup>\u00ae<\/sup><\/strong><\/a>) under hydrated conditions, simulating the physiologically relevant environment of clinical periodontal and soft tissue applications.<\/p>\n<\/div><div class=\"fusion-text fusion-text-2\"><p><strong>STUDY DESIGN<\/strong><\/p>\n<p data-prosemirror-content-type=\"node\" data-prosemirror-node-name=\"paragraph\" data-prosemirror-node-block=\"true\"><a href=\"https:\/\/botiss.com\/product\/mucoderm\/\" target=\"_blank\" rel=\"noopener\"><strong data-prosemirror-content-type=\"mark\" data-prosemirror-mark-name=\"strong\">mucoderm<sup>\u00ae<\/sup><\/strong><\/a> was hydrated in sterile 0.9% NaCl solution. AFM analysis (EasyScan 2 system, Dynamic Force\/Non-Contact mode) was performed on 5 \u00d7 5 \u00b5m scan areas in wet conditions. Evaluated parameters included height (topography), deflection signal, 3D reconstruction, surface profiles, quantitative roughness (Sa, Sq, Sz, Ssk, Sku), and height distribution histograms. Samples were mounted on poly-L-lysine-coated slides for stability.<\/p>\n<\/div><div class=\"fusion-text fusion-text-3\"><p><strong>KEY FINDINGS<\/strong><\/p>\n<ul>\n<li>The hydrated <strong data-prosemirror-content-type=\"mark\" data-prosemirror-mark-name=\"strong\">mucoderm<sup>\u00ae<\/sup><\/strong> matrix exhibited a <strong>continuous, moderately undulating surface<\/strong> with homogeneous distribution of rounded elevations and depressions, consistent with an isotropic collagen network and no detectable structural defects or abrupt discontinuities.<\/li>\n<li>Deflection imaging highlighted local slope variations and microstructural heterogeneities.<\/li>\n<li>3D reconstructions confirmed uniform spatial organization with gradual height transitions.<\/li>\n<li>Quantitative roughness parameters showed moderate values: <strong>Sa = 0.1179 \u00b5m<\/strong>, <strong>Sq = 0.1765 \u00b5m<\/strong>, <strong>Sz = 1.541 \u00b5m<\/strong>. Height distribution was centered around the mean plane with controlled dispersion.<\/li>\n<\/ul>\n<\/div><div class=\"fusion-text fusion-text-4\"><p><strong>CONCLUSION<\/strong><\/p>\n<p>Under hydrated conditions, <a href=\"https:\/\/botiss.com\/product\/mucoderm\/\" target=\"_blank\" rel=\"noopener\"><strong data-prosemirror-content-type=\"mark\" data-prosemirror-mark-name=\"strong\">mucoderm<sup>\u00ae<\/sup><\/strong><\/a> presents a stable, continuous, and moderately rough nanoscale surface morphology that supports favorable biological interactions, including protein adsorption, cell adhesion, and tissue integration. These features reflect stable structural behavior and suggest surface properties highly compatible with hydrated environments, providing favorable implications for soft tissue adaptation and clinical performance.<\/p>\n<p>This AFM characterization provides valuable nanoscale insights into <a href=\"https:\/\/botiss.com\/product\/mucoderm\/\" target=\"_blank\" rel=\"noopener\"><strong data-prosemirror-content-type=\"mark\" data-prosemirror-mark-name=\"strong\">mucoderm<sup>\u00ae<\/sup><\/strong><\/a><strong>\u2019s<\/strong> surface behavior in physiologically relevant conditions.<\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":72868,"template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"product_brand":[],"product_cat":[327],"product_tag":[199,125],"class_list":["post-72865","product","type-product","status-publish","has-post-thumbnail","product_cat-studies","product_tag-mucoderm","product_tag-soft-tissue-management","first","instock","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v28.5) - 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