{"id":31598,"date":"2024-02-06T16:41:36","date_gmt":"2024-02-06T15:41:36","guid":{"rendered":"https:\/\/botiss.com\/?p=31598"},"modified":"2024-02-06T16:41:36","modified_gmt":"2024-02-06T15:41:36","slug":"dental-health-immune-system-and-bones-vitamin-d-and-its-positive-influence-on-the-body","status":"publish","type":"post","link":"https:\/\/botiss.com\/it\/dental-health-immune-system-and-bones-vitamin-d-and-its-positive-influence-on-the-body\/","title":{"rendered":"Dental health, immune system and bones – vitamin D and its positive influence on the body"},"content":{"rendered":"

The current study situation clearly shows how diverse the effect of vitamin D can be. Various diseases such as cancer, cardiovascular diseases and neurological disorders are often associated with a vitamin D deficiency 1<\/sup>. <\/strong><\/span><\/p>\n

Vitamin D plays a significant role in health by contributing to the regulation of a healthy immune system and the maintenance of defense functions 2,3<\/sup>. Furthermore, vitamin D is of immense importance for calcium balance and bone metabolism and supports intestinal calcium absorption 4<\/sup>. An adequate supply of the steroid hormone therefore helps to prevent osteoporosis 5<\/sup>. Conversely, a severe vitamin D deficiency impairs adequate tooth growth and the correct formation of tooth enamel 6,7<\/sup>. It is therefore all the more important to have an adequate vitamin D level and, if necessary, to supplement it in order to promote remineralization of the tooth surface and correct tooth growth 8<\/sup>.<\/p>\n

People with inadequate vitamin D levels are also more likely to have poorer periodontal health and more inflammation 9<\/sup>. These inflammatory events are detectable in saliva, which contains more inflammatory markers when vitamin D deficiency is present 10<\/sup>. This further emphasizes the potential of vitamin D to prevent periodontal inflammation. Especially in the defense against disease-causing pathogens, the steroid hormone is able to stimulate the production of antimicrobial peptides, thus supporting the body’s defense functions and potentially preventing the formation of harmful plaque 11,12<\/sup>. Vitamin D also influences tissue growth, angiogenesis and inflammatory processes in cancer cells, so that vitamin D with its anti-proliferative and anti-inflammatory properties could possibly slow down the progression of cancer 13,14<\/sup>. Even in the orthodontic field, vitamin D is becoming increasingly important, as more and more studies suggest the influence of vitamin D on tooth movement 15,16<\/sup>.<\/p>\n

In summary, it can be shown that an adequate vitamin D level is important for bone remodeling and the immune system. It is therefore crucial to adjust vitamin D levels to enable optimal bone health and regeneration.<\/p>\n

Literature<\/strong><\/p>\n

    \n
  1. Wang, H. et al.<\/em> Vitamin D and Chronic Diseases. Aging Dis<\/em> 8<\/strong>, 346 (2017).<\/li>\n
  2. Ao, T., Kikuta, J. & Ishii, M. The Effects of Vitamin D on Immune System and Inflammatory Diseases. Biomolecules<\/em> 11<\/strong>, (2021).<\/li>\n
  3. Charoenngam, N. & Holick, M. F. Immunologic Effects of Vitamin D on Human Health and Disease. Nutrients<\/em> 12<\/strong>, 2097 (2020).<\/li>\n
  4. Fleet, J. C. The Role of Vitamin D in the Endocrinology Controlling Calcium Homeostasis. Mol Cell Endocrinol<\/em> 453<\/strong>, 36 (2017).<\/li>\n
  5. Khazai, N., Judd, S. E. & Tangpricha, V. Calcium and Vitamin D: Skeletal and Extraskeletal Health. Curr Rheumatol Rep<\/em> 10<\/strong>, 110 (2008).<\/li>\n
  6. Botelho, J., Machado, V., Proen\u00e7a, L., Delgado, A. S. & Mendes, J. J. Vitamin D deficiency and oral health: A comprehensive review. Nutrients<\/em> vol. 12 Preprint at https:\/\/doi.org\/10.3390\/nu12051471 (2020).<\/li>\n
  7. Al-Jubori, S. H., AL-Murad, M. A. & Al-Mashhadane, F. A. Effect of Oral Vitamin D3 on Dental Caries: An In-Vivo and In-Vitro Study. Cureus<\/em> 14<\/strong>, (2022).<\/li>\n
  8. Vitamin D: Unveiling the Crucial Trifecta – Teeth, Immune System, and Bones. https:\/\/www.oralhealthgroup.com\/features\/vitamin-d-unveiling-the-crucial-trifecta-teeth-immune-system-and-bones\/.<\/li>\n
  9. Machado, V., Lobo, S., Proen\u00e7a, L., Mendes, J. J. & Botelho, J. Vitamin D and Periodontitis: A Systematic Review and Meta-Analysis. Nutrients<\/em> 12<\/strong>, 1\u201317 (2020).<\/li>\n
  10. Jagelavi\u010dien\u0117, E., Vaitkevi\u010dien\u0117, I., \u0160ilingait\u0117, D., \u0160ink\u016bnait\u0117, E. & Daug\u0117lait\u0117, G. The Relationship between Vitamin D and Periodontal Pathology. Medicina (B Aires)<\/em> 54<\/strong>, (2018).<\/li>\n
  11. Hamza, F. N. et al.<\/em> Immunomodulatory Properties of Vitamin D in the Intestinal and Respiratory Systems. Nutrients<\/em> 15<\/strong>, 1696 (2023).<\/li>\n
  12. Khurshid, Z. et al.<\/em> Oral antimicrobial peptides: Types and role in the oral cavity. Saudi Pharmaceutical Journal\u202f: SPJ<\/em> 24<\/strong>, 515 (2016).<\/li>\n
  13. Hung, M., Almpani, K., Thao, B., Sudweeks, K. & Lipsky, M. S. Vitamin D in the Prevention and Treatment of Oral Cancer: A Scoping Review. Nutrients 2023, Vol. 15, Page 2346<\/em> 15<\/strong>, 2346 (2023).<\/li>\n
  14. Feldman, D., Krishnan, A. V., Swami, S., Giovannucci, E. & Feldman, B. J. The role of vitamin D in reducing cancer risk and progression. Nature Reviews Cancer 2014 14:5<\/em> 14<\/strong>, 342\u2013357 (2014).<\/li>\n
  15. Almoammar, K. Vitamin D and orthodontics: an insight review. Clin Cosmet Investig Dent<\/em> 10<\/strong>, 165 (2018).<\/li>\n
  16. Khalaf, R. M. & Almudhi, A. A. Effects of vitamin D deficiency on the rate of orthodontic tooth movement: An animal study. Saudi Dent J<\/em> 34<\/strong>, 129 (2022).<\/li>\n<\/ol>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"

    The current study situation clearly shows how diverse the effect of vitamin D can be. Various diseases such as cancer, cardiovascular diseases and neurological disorders are often associated with a vitamin D deficiency.<\/p>\n","protected":false},"author":2,"featured_media":31601,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"categories":[1045],"tags":[],"class_list":["post-31598","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-news"],"acf":[],"yoast_head":"\nDental health, immune system and bones - vitamin D and its positive influence on the body - botiss biomaterials GmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/botiss.com\/it\/dental-health-immune-system-and-bones-vitamin-d-and-its-positive-influence-on-the-body\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Dental health, immune system and bones - vitamin D and its positive influence on the body\" \/>\n<meta property=\"og:description\" content=\"The current study situation clearly shows how diverse the effect of vitamin D can be. 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