{"id":11880,"date":"2019-02-04T20:31:08","date_gmt":"2019-02-04T19:31:08","guid":{"rendered":"https:\/\/botiss.com\/product\/lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial\/"},"modified":"2024-07-24T10:00:10","modified_gmt":"2024-07-24T08:00:10","slug":"lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial","status":"publish","type":"product","link":"https:\/\/botiss.com\/it\/prodotto\/lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial\/","title":{"rendered":"Lateral Ramus Cortical Bone Plate in Alveolar Cleft Osteoplasty with Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone: Phase I Clinical Trial"},"content":{"rendered":"<h4><strong><span style=\"color: #00ccff;\">Khojasteh A, Kheiri L, Behnia H, Tehranchi A, Nazeman P, Nadjmi N, and Soleimani M. Biomed Res Int. 2017; 2017:6560234.<\/span><\/strong><\/h4>\n<h4><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29379800\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"color: #000000;\">https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29379800<\/span><\/a><\/h4>\n<p><span style=\"color: #000000;\"><strong>Tissue regeneration has become a promising treatment for craniomaxillofacial bone defects such as alveolar clefts. This study sought to assess the efficacy of lateral ramus cortical plate with buccal fat pad derived mesenchymal stem cells (BFSCs) in treatment of human alveolar cleft defects.<\/strong><\/span><\/p>\n<p><span style=\"color: #00ccff;\">Methods:<\/span><\/p>\n<p>Ten patients with unilateral anterior maxillary cleft met the inclusion criteria and were assigned to three treatment groups. 1) anterior iliac crest (AIC) bone Jason\u00ae membrane (AIC group), 2) with lateral ramus cortical bone plate (LRCP) with BFSCs mounted on a natural bovine bone mineral (LRCP+BFSC), and 3) with AIC bone, BFSCs cultured on natural bovine bone mineral, and Jason\u00ae membrane (AIC+BFSC).<\/p>\n<p><span style=\"color: #00ccff;\">Results \/ <\/span><span style=\"color: #00ccff;\">Conclusion:<\/span><\/p>\n<p>2) LRCP+BFSC group demonstrated defect closure and higher amounts of new bone formation but less than 3) AIC+BFSC suggesting that use of BFSCs within LRCP cage and AIC may enhance bone regeneration in alveolar cleft bone defects.<\/p>\n<p><span style=\"color: #00ccff;\">Arash Khojasteh<br \/>\n<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Khojasteh A, Kheiri L, Behnia H, Tehranchi A, Nazeman P, Nadjmi N, and Soleimani M. Biomed Res Int. 2017; 2017:6560234. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29379800 Tissue regeneration has become a promising treatment for craniomaxillofacial  &#8230;<\/p>\n","protected":false},"featured_media":11881,"template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"product_brand":[],"product_cat":[2063,2059],"product_tag":[1933,1902,1931],"class_list":["post-11880","product","type-product","status-publish","has-post-thumbnail","product_cat-scienza","product_cat-studi","product_tag-cerabone-it","product_tag-membrana-jason-it","product_tag-ricostruzione-del-crinale","first","instock","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Lateral Ramus Cortical Bone Plate in Alveolar Cleft Osteoplasty with Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone: Phase I Clinical Trial - botiss biomaterials GmbH<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/botiss.com\/it\/prodotto\/lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial\/\" \/>\n<meta property=\"og:locale\" content=\"it_IT\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Lateral Ramus Cortical Bone Plate in Alveolar Cleft Osteoplasty with Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone: Phase I Clinical Trial\" \/>\n<meta property=\"og:description\" content=\"Khojasteh A, Kheiri L, Behnia H, Tehranchi A, Nazeman P, Nadjmi N, and Soleimani M. Biomed Res Int. 2017; 2017:6560234. https:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29379800 Tissue regeneration has become a promising treatment for craniomaxillofacial ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/botiss.com\/it\/prodotto\/lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial\/\" \/>\n<meta property=\"og:site_name\" content=\"botiss biomaterials GmbH\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/botissdental\" \/>\n<meta property=\"article:modified_time\" content=\"2024-07-24T08:00:10+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/02\/PUBLICATIONS_10.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1200\" \/>\n\t<meta property=\"og:image:height\" content=\"800\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:site\" content=\"@BotissB\" \/>\n<meta name=\"twitter:label1\" content=\"Tempo di lettura stimato\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minuto\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/botiss.com\\\/it\\\/prodotto\\\/lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial\\\/\",\"url\":\"https:\\\/\\\/botiss.com\\\/it\\\/prodotto\\\/lateral-ramus-cortical-bone-plate-in-alveolar-cleft-osteoplasty-with-concomitant-use-of-buccal-fat-pad-derived-cells-and-autogenous-bone-phase-i-clinical-trial\\\/\",\"name\":\"Lateral Ramus Cortical Bone Plate in Alveolar Cleft Osteoplasty with Concomitant Use of Buccal Fat Pad Derived Cells and Autogenous Bone: Phase I Clinical Trial - 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