{"id":16865,"date":"2022-03-11T10:25:58","date_gmt":"2022-03-11T09:25:58","guid":{"rendered":"https:\/\/botiss.com\/product\/case-report-blaskovic\/"},"modified":"2023-09-08T09:55:44","modified_gmt":"2023-09-08T07:55:44","slug":"posterior-mandible-reconstruction-using-cerabone-plus-permamem-and-mucoderm-a-case-report","status":"publish","type":"product","link":"https:\/\/botiss.com\/it\/prodotto\/posterior-mandible-reconstruction-using-cerabone-plus-permamem-and-mucoderm-a-case-report\/","title":{"rendered":"Posterior mandible reconstruction using cerabone\u00ae +HyA, permamem\u00ae and mucoderm\u00ae \u2013 A case report"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:1200px;margin-left: calc(-0% \/ 2 );margin-right: calc(-0% \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:0px;--awb-spacing-right-large:0%;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:0%;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:0%;--awb-spacing-left-small:0%;\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1\"><p><b>The presented case describes the rehabilitation of a challenging extended edentulous site in the posterior lower jaw, using state-of the-art bone regeneration- and soft tissue management techniques, with the goal to bring back the patient a long-term stable dentition.<\/b><\/p>\n<\/div><div class=\"fusion-title title fusion-title-1 fusion-sep-none fusion-title-text fusion-title-size-five\" style=\"--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:0px;--awb-margin-left-small:0px;\"><h5 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:18;line-height:var(--awb-typography1-line-height);\"><strong>INITIAL SITUATION<\/strong><\/h5><\/div><div class=\"fusion-text fusion-text-2\"><p>A female patient (66 years old) came to the clinic requesting a periodontal treatment. The patient was in healthy condition, without taking medication and was a non-smoker. She was already missing tooth #36, #37 and #25 (Fig. 1 and 2). After initial periodontal treatment, revaluation and maintenance therapy, the patient requested to restore the missing teeth. The tooth gap at position #36 and #37 impaired the patient\u2019s ability to chew and was therefore primarily of functional concern.<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-1 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-2 fusion-gallery-layout-grid fusion-gallery-1\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01.jpg\" data-caption=\"Fig. 1 Initial situation showing reduced bone volume in region #36 and #37.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_1]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_01.jpg\" aria-label=\"Case_Report_Blaskovic_marko_01.jpg\" class=\"img-responsive wp-image-16868\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_01.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02.jpg\" data-caption=\"Fig. 2 Initial situation in region #36 and #37. Reduced keratinized mucosa width before the treatment.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_1]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_02.jpg\" aria-label=\"Case_Report_Blaskovic_marko_02.jpg\" class=\"img-responsive wp-image-16870\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_02.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><\/div><\/div><div class=\"fusion-title title fusion-title-2 fusion-sep-none fusion-title-text fusion-title-size-five\" style=\"--awb-margin-top:5%;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:0px;--awb-margin-left-small:0px;\"><h5 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:18;line-height:var(--awb-typography1-line-height);\"><b>TREATMENT PLANNING<\/b><\/h5><\/div><div class=\"fusion-text fusion-text-3\"><p>After CBCT assessment (Fig. 3 and 4), implant placement and simultaneous GBR was proposed to the patient. Since three defects were expected to occur around the implant (buccal and lingual dehiscence and a small two to three millimetre vertical defect on the distal side of the implant), a non-resorbable membrane (permamem<sup>\u00ae<\/sup>) was planned to be used, which would provide sufficient form stability and thus optimal conditions for complete defect resolution. A combination of autogenous graft and a volume stable bone substitute (cerabone<sup>\u00ae<\/sup> +HyA) were planned to be used as a bone graft. The autogenous bone would be collected with a bone scraper form the retromolar region adjacent to the defect site. Finally, a soft tissue management procedure will be planned prior to the restorative work.<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-2 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-2 fusion-gallery-layout-grid fusion-gallery-2\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03.jpg\" data-caption=\"Fig. 3 Detailed evaluation of region #36 and #37.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_2]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_03.jpg\" aria-label=\"Case_Report_Blaskovic_marko_03.jpg\" class=\"img-responsive wp-image-16872\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_03.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04.jpg\" data-caption=\"Fig. 4 Combined horizontal and vertical defect.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_2]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_04\" aria-label=\"Case_Report_Blaskovic_marko_04\" class=\"img-responsive wp-image-16866\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_04.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><\/div><\/div><div class=\"fusion-title title fusion-title-3 fusion-sep-none fusion-title-text fusion-title-size-five\" style=\"--awb-margin-top:5%;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:0px;--awb-margin-left-small:0px;\"><h5 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:18;line-height:var(--awb-typography1-line-height);\"><b>SURGICAL AND PROSTHETIC PROCEDURE<\/b><\/h5><\/div><div class=\"fusion-text fusion-text-4\"><p><strong>Implant placement and GBR<\/strong><\/p>\n<p>A full thickness flap was raised with a vertical incision. The incision was elongated in the distal direction in order to include the retromolar region (Fig. 5). Then the patient underwent an atraumatic extraction of tooth number #38 as the tooth showed a poor perio prognosis with deep pockets and resorption more than half to two-thirds of the root length. Thereafter, a 4.1 x 10 BLT Straumann bone level implant was placed and, as expected, three peri-implant defects were present (Fig. 6 \u2013 8). Cortical perforations were performed on the buccal aspect. The membrane (permamem<sup>\u00ae<\/sup>, 20 x 30 mm) was trimmed according to the defect size and initially stabilised in the apical part of the membrane. Subsequently a bone graft was placed: for the first layer only autogenous bone was used, which was harvested from the retromolar area (Fig. 9 \u2013 11) and packed around the exposed implant surface (Fig. 12). For the second layer a mixture of 50% autogenous bone and 50% cerabone<sup>\u00ae<\/sup> +HyA was used (Fig. 13). The second layer was used on top of the first layer. Afterwards, the membrane was placed over the graft, tightly adapted and completely stabilized with additional bone pins (Fig. 14). 6.0 monofilament resorbable mattress sutures were used to achieve primary and tension-free wound closure (Fig. 15).<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-3 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-11 fusion-gallery-layout-grid fusion-gallery-3\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05.jpg\" data-caption=\"Fig. 5 After flap elevation and extraction of tooth #38.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_05.jpg\" aria-label=\"Case_Report_Blaskovic_marko_05.jpg\" class=\"img-responsive wp-image-16874\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_05.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06.jpg\" data-caption=\"Fig. 6 After implant placement.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_06.jpg\" aria-label=\"Case_Report_Blaskovic_marko_06.jpg\" class=\"img-responsive wp-image-16876\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_06.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07.jpg\" data-caption=\"Fig. 7 Peri-implant bone deficiency with buccal and lingual dehiscence, and vertical defect.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_07.jpg\" aria-label=\"Case_Report_Blaskovic_marko_07.jpg\" class=\"img-responsive wp-image-16878\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_07.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08.jpg\" data-caption=\"Fig. 8 Occlusal view.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_08.jpg\" aria-label=\"Case_Report_Blaskovic_marko_08.jpg\" class=\"img-responsive wp-image-16880\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_08.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09.jpg\" data-caption=\"Fig. 9 Donor site for bone grafting in the retromolar area.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_09.jpg\" aria-label=\"Case_Report_Blaskovic_marko_09.jpg\" class=\"img-responsive wp-image-16882\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_09.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10.jpg\" data-caption=\"Fig. 10 Minimal trauma in the donor site-retromolar region.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_10.jpg\" aria-label=\"Case_Report_Blaskovic_marko_10.jpg\" class=\"img-responsive wp-image-16884\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_10.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11.jpg\" data-caption=\"Fig. 11 Autogenous bone graft.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_11.jpg\" aria-label=\"Case_Report_Blaskovic_marko_11.jpg\" class=\"img-responsive wp-image-16886\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_11.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12.jpg\" data-caption=\"Fig. 12 Initial fixation of permamem\u00ae. Autogenous bone as the first layer of the graft.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_12.jpg\" aria-label=\"Case_Report_Blaskovic_marko_12.jpg\" class=\"img-responsive wp-image-16888\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_12.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13.jpg\" data-caption=\"Fig. 13 Second layer 50% autogenous bone and 50% cerabone\u00ae +HyA.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_13.jpg\" aria-label=\"Case_Report_Blaskovic_marko_13.jpg\" class=\"img-responsive wp-image-16890\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_13.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14.jpg\" data-caption=\"Fig. 14 permamem\u00ae placed over the grafted site and stabilized with titanium pins.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_14.jpg\" aria-label=\"Case_Report_Blaskovic_marko_14.jpg\" class=\"img-responsive wp-image-16892\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_14.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15.jpg\" data-caption=\"Fig. 15 Primary wound closure.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_3]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_15.jpg\" aria-label=\"Case_Report_Blaskovic_marko_15.jpg\" class=\"img-responsive wp-image-16894\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_15.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><\/div><\/div><div class=\"fusion-text fusion-text-5\" style=\"--awb-margin-top:5%;\"><p><strong>Re-entry<\/strong><\/p>\n<p>After six months of healing time, the treated site presented with excellent soft tissue healing (Fig. 19) and was reopened with a full thickness flap and the non-resorbable membrane was removed (Fig. 16 and 17). The re-entered site showed optimal graft integration with a sufficient bone gain both in horizontal and vertical dimension (Fig. 17 and 18). However, displacement of the mucogingival line and a reduced width of the keratinized mucosa was evident (Fig. 19).<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-4 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-4 fusion-gallery-layout-grid fusion-gallery-4\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16.jpg\" data-caption=\"Fig. 16 Removal of permamem\u00ae.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_4]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_16.jpg\" aria-label=\"Case_Report_Blaskovic_marko_16.jpg\" class=\"img-responsive wp-image-16896\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_16.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17.jpg\" data-caption=\"Fig. 17 Regenerated site after membrane reflection.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_4]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_17.jpg\" aria-label=\"Case_Report_Blaskovic_marko_17.jpg\" class=\"img-responsive wp-image-16898\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_17.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18.jpg\" data-caption=\"Fig. 18 CBCT at re-entry.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_4]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_18.jpg\" aria-label=\"Case_Report_Blaskovic_marko_18.jpg\" class=\"img-responsive wp-image-16900\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_18.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19.jpg\" data-caption=\"Fig. 19 Soft tissue situation before re-entry.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_4]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_19.jpg\" aria-label=\"Case_Report_Blaskovic_marko_19.jpg\" class=\"img-responsive wp-image-16902\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_19.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><\/div><\/div><div class=\"fusion-text fusion-text-6\" style=\"--awb-margin-top:5%;\"><p><strong>Soft tissue management<\/strong><\/p>\n<p>Two months after re-entry and membrane removal, a widening of the keratinized mucosa was performed: an apically positioned flap was combined with a free gingival graft. The graft was taken from the distal part of the palate (Fig. 20 \u2013 22).<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-5 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-3 fusion-gallery-layout-grid fusion-gallery-5\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20.jpg\" data-caption=\"Fig. 20 Situation 2 months after removal of the membrane.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_5]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_20.jpg\" aria-label=\"Case_Report_Blaskovic_marko_20.jpg\" class=\"img-responsive wp-image-16904\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_20.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21.jpg\" data-caption=\"Fig. 21 Apically displaced flap.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_5]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_21.jpg\" aria-label=\"Case_Report_Blaskovic_marko_21.jpg\" class=\"img-responsive wp-image-16906\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_21.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22.jpg\" data-caption=\"Fig. 22 Free gingival graft stabilized on the exposed periostal surface.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_5]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_22.jpg\" aria-label=\"Case_Report_Blaskovic_marko_22.jpg\" class=\"img-responsive wp-image-16908\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_22.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><\/div><\/div><div class=\"fusion-text fusion-text-7\" style=\"--awb-margin-top:5%;\"><p>Two months after the third procedure, a sufficient gain of keratinized tissue could be achieved (Fig. 23 and 24). Then, the implant uncovering procedure was performed with simultaneous peri-implant soft tissue augmentation. In order to avoid a second harvesting procedure from the palate, a porcine acellular dermal matrix (mucoderm<sup>\u00ae<\/sup>) was used instead. The matrix was hydrated in sterile saline solution and placed at the buccal aspect. The marginal soft tissues were sutured using 6.0 non-resorbable monofilament sutures (Fig. 25 \u2013 27).<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-6 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-5 fusion-gallery-layout-grid fusion-gallery-6\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23.jpg\" data-caption=\"Fig. 23 Soft tissue situation 2 months later.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_6]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_23.jpg\" aria-label=\"Case_Report_Blaskovic_marko_23.jpg\" class=\"img-responsive wp-image-16910\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_23.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24.jpg\" data-caption=\"Fig. 24 Lateral view showing adequate keratinized tissue width.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_6]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_24.jpg\" aria-label=\"Case_Report_Blaskovic_marko_24.jpg\" class=\"img-responsive wp-image-16912\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_24.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25.jpg\" data-caption=\"Fig. 25 Augmentation of soft tissue thickness with mucoderm\u00ae.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_6]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_25.jpg\" aria-label=\"Case_Report_Blaskovic_marko_25.jpg\" class=\"img-responsive wp-image-16914\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_25.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26.jpg\" data-caption=\"Fig. 26 Suturing to cover mucoderm\u00ae by the flap and to stabilize the treated site.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_6]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_26.jpg\" aria-label=\"Case_Report_Blaskovic_marko_26.jpg\" class=\"img-responsive wp-image-16916\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_26.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27.jpg\" data-caption=\"Fig. 27 Occlusal view.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_6]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_27.jpg\" aria-label=\"Case_Report_Blaskovic_marko_27.jpg\" class=\"img-responsive wp-image-16918\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_27.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><\/div><\/div><div class=\"fusion-text fusion-text-8\" style=\"--awb-margin-top:5%;\"><p>Six weeks after healing abutment placement, a provisional crown was fabricated. The provisional crown was used to condition the soft tissue and obtain a more natural emergence profile (Fig. 28 \u2013 31).<\/p>\n<\/div><div class=\"awb-gallery-wrapper awb-gallery-wrapper-7 button-span-no\"><div style=\"margin:-13px;--awb-bordersize:0px;--awb-border-radius:8px;--awb-caption-title-size:0px;--awb-caption-margin-top:10px;\" class=\"fusion-gallery fusion-gallery-container fusion-grid-2 fusion-columns-total-5 fusion-gallery-layout-grid fusion-gallery-7\"><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28.jpg\" data-caption=\"Fig. 28 Situation 6 weeks after placement of the healing abutment.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_7]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_28.jpg\" aria-label=\"Case_Report_Blaskovic_marko_28.jpg\" class=\"img-responsive wp-image-16920\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_28.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29.jpg\" data-caption=\"Fig. 29 Occlusal view.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_7]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_29.jpg\" aria-label=\"Case_Report_Blaskovic_marko_29.jpg\" class=\"img-responsive wp-image-16922\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_29.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30.jpg\" data-caption=\"Fig. 30 Provisional screw retained crown.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_7]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_30.jpg\" aria-label=\"Case_Report_Blaskovic_marko_30.jpg\" class=\"img-responsive wp-image-16924\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_30.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31.jpg\" data-caption=\"Fig. 31 Provisional crown in situ.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_7]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_31.jpg\" aria-label=\"Case_Report_Blaskovic_marko_31.jpg\" class=\"img-responsive wp-image-16926\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_31.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div style=\"padding:13.5px;\" class=\"fusion-grid-column fusion-gallery-column fusion-gallery-column-2 hover-type-none\"><div class=\"fusion-gallery-image\"><a href=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32.jpg\" data-caption=\"Fig. 32 Final restoration.\" rel=\"noreferrer\" data-rel=\"iLightbox[gallery_image_7]\" class=\"fusion-lightbox\" target=\"_self\"><img decoding=\"async\" src=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32.jpg\" width=\"1200\" height=\"800\" alt=\"\" title=\"Case_Report_Blaskovic_marko_32.jpg\" aria-label=\"Case_Report_Blaskovic_marko_32.jpg\" class=\"img-responsive wp-image-16928\" srcset=\"https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32-200x133.jpg 200w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32-400x267.jpg 400w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32-600x400.jpg 600w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32-800x533.jpg 800w, https:\/\/botiss.com\/wp-content\/uploads\/2023\/03\/Case_Report_Blaskovic_marko_32.jpg 1200w\" sizes=\"(min-width: 2200px) 100vw, (min-width: 712px) 594px, (min-width: 640px) 712px, \" \/><\/a><\/div><\/div><div class=\"clearfix\"><\/div><\/div><\/div><div class=\"fusion-title title fusion-title-4 fusion-sep-none fusion-title-text fusion-title-size-five\" style=\"--awb-margin-top:5%;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:0px;--awb-margin-left-small:0px;\"><h5 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:18;line-height:var(--awb-typography1-line-height);\"><b>FINAL SCORE<\/b><\/h5><\/div><div class=\"fusion-text fusion-text-9\"><p>A screw retained monolithic ceramic zirconia crown (on Variobase link) was created as definitive restoration (Fig. 32). The bone augmentation procedure allowed the fulfilment of two important goals: 1) prosthetically driven implant placement, which enables fabrication of a screw retained crown and 2) bony walls of adequate thickness (minimum of two millimetres) surrounding the implant. Soft tissue augmentation procedures recreated the peri-implant soft tissue of adequate quality (two millimetres keratinized soft tissue) and thickness (at least two millimetres), which has a positive long-term effect providing peri-implant soft tissue and marginal bone stability and facilitating the maintenance of oral hygiene.<span class=\"Apple-converted-space\">\u00a0<\/span><\/p>\n<\/div><div class=\"fusion-title title fusion-title-5 fusion-sep-none fusion-title-text fusion-title-size-five\" style=\"--awb-margin-top:5%;--awb-margin-top-small:0px;--awb-margin-right-small:0px;--awb-margin-bottom-small:0px;--awb-margin-left-small:0px;\"><h5 class=\"fusion-title-heading title-heading-left fusion-responsive-typography-calculated\" style=\"margin:0;--fontSize:18;line-height:var(--awb-typography1-line-height);\"><b>CONCLUSION<\/b><\/h5><\/div><div class=\"fusion-text fusion-text-10\"><p>The fulfilment of all aforementioned points is especially important in periodontally compromised patients, who have an increased risk for developing peri-implantitis. A detailed clinical diagnosis and treatment planning together with the selection of suitable biomaterials is key for achieving a satisfying outcome both on a functional and aesthetic level.<\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":16866,"template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"product_brand":[],"product_cat":[170],"product_tag":[377,383,347,380],"class_list":["post-16865","product","type-product","status-publish","has-post-thumbnail","product_cat-fallberichte","product_tag-cerabone-hya-de","product_tag-mucoderm-de","product_tag-permamem-de","product_tag-ridge-augmentation-reconstruction-de","first","instock","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>Posterior mandible reconstruction using cerabone\u00ae +HyA, permamem\u00ae and mucoderm\u00ae \u2013 A case report - 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