{"id":24968,"date":"2023-10-11T10:47:35","date_gmt":"2023-10-11T08:47:35","guid":{"rendered":"https:\/\/botiss.com\/?post_type=product&#038;p=24968"},"modified":"2026-02-09T14:02:19","modified_gmt":"2026-02-09T13:02:19","slug":"first-clinical-case-report-on-alveolar-ridge-augmentation-using-a-bovine-bone-substitute-with-hyaluronate-cerabone-plus-combined-with-allogeneic-bone-granules-maxgraft","status":"publish","type":"product","link":"https:\/\/botiss.com\/it\/prodotto\/first-clinical-case-report-on-alveolar-ridge-augmentation-using-a-bovine-bone-substitute-with-hyaluronate-cerabone-plus-combined-with-allogeneic-bone-granules-maxgraft\/","title":{"rendered":"First Clinical Case Report on Alveolar Ridge Augmentation Using a Bovine Bone Substitute with Hyaluronate (cerabone\u00ae +HyA) Combined with Allogeneic Bone Granules (maxgraft\u00ae)"},"content":{"rendered":"<div class=\"fusion-fullwidth fullwidth-box fusion-builder-row-1 fusion-flex-container nonhundred-percent-fullwidth non-hundred-percent-height-scrolling\" style=\"--awb-border-radius-top-left:0px;--awb-border-radius-top-right:0px;--awb-border-radius-bottom-right:0px;--awb-border-radius-bottom-left:0px;--awb-flex-wrap:wrap;\" ><div class=\"fusion-builder-row fusion-row fusion-flex-align-items-flex-start fusion-flex-content-wrap\" style=\"max-width:calc( 1200px + 0px );margin-left: calc(-0px \/ 2 );margin-right: calc(-0px \/ 2 );\"><div class=\"fusion-layout-column fusion_builder_column fusion-builder-column-0 fusion_builder_column_1_1 1_1 fusion-flex-column\" style=\"--awb-bg-blend:overlay;--awb-bg-size:cover;--awb-width-large:100%;--awb-margin-top-large:30px;--awb-spacing-right-large:0px;--awb-margin-bottom-large:0px;--awb-spacing-left-large:0px;--awb-width-medium:100%;--awb-order-medium:0;--awb-spacing-right-medium:0px;--awb-spacing-left-medium:0px;--awb-width-small:100%;--awb-order-small:0;--awb-spacing-right-small:0px;--awb-spacing-left-small:0px;\" data-scroll-devices=\"small-visibility,medium-visibility,large-visibility\"><div class=\"fusion-column-wrapper fusion-column-has-shadow fusion-flex-justify-content-flex-start fusion-content-layout-column\"><div class=\"fusion-text fusion-text-1\" style=\"--awb-text-transform:none;\"><p><strong>Original title: First Clinical Case Report of a Xenograft\u2013Allograft Combination for Alveolar Ridge Augmentation Using a Bovine Bone Substitute Material with Hyaluronate (Cerabone\u00ae +HyA) Combined with Allogeneic Bone Granules (Maxgraft\u00ae).<\/strong><br \/>\n<span style=\"color: #00ccff;\"><strong>Kloss, F.R.; K\u00e4mmerer, P.W.; Kloss-Brandst\u00e4tter, A. J. Clin. Med. 2023, 12, 6214.<\/strong><\/span><br \/>\n<strong><a href=\"https:\/\/doi.org\/10.3390\/jcm12196214\" target=\"_blank\" rel=\"noopener\">https:\/\/doi.org\/10.3390\/jcm12196214<\/a> <\/strong><\/p>\n<p><strong>This case report demonstrates Guided Bone Regeneration for later implant placement in the aesthetic zone in a 34-year-old patient using a combination of freeze-dried bone allograft and pure bovine bone mineral with hyaluronate.<\/strong><\/p>\n<p><strong>INITITAL SITUATION<\/strong><\/p>\n<p>Tooth 21 suffered from a trauma 15 years ago and was mobile. Panoramic x-ray demonstrated a periradicular lesion, and the clinical examination revealed the presence of a buccal fistula. Therefore, the tooth was extracted. A slight lack of buccal bone was evident; however, the soft tissue situation was inflammation-free, and a broad zone of keratinized gingiva was visible. Otherwise, the patient was healthy without any symptoms of periodontitis.<\/p>\n<p><strong>TREATMENT APPROACH<\/strong><\/p>\n<p>CBCT analysis showed a transverse bone defect of the alveolar ridge with a residual ridge width of 2\u20133 mm. Based on the geometry of the defect a two-stage Guided Bone Regeneration (GBR) procedure was planned using bovine bone mineral with hyaluronate (cerabone\u00ae +HyA) mixed with allograft bone substitute from human donor bone (maxgraft\u00ae cancellous granules) in conjunction with a porcine pericardium membrane (Jason\u00ae membrane). Implant placement was planned six months post-augmentation.<\/p>\n<p><strong>OUTCOME<\/strong><\/p>\n<p>The healing was uneventful without signs of infection, wound dehiscence, graft exposure or other postoperative complications. Six months post-surgery, re-entry and implant placement were performed. The bleeding bone indicated satisfactory osseous transformation and good blood supply to the graft. Moreover, the biomaterials mix of xeno- and allograft was well integrated into the recipient site, and the formerly lacking bone volume was sufficiently restored. A titanium implant (Medentika; Straumann Group) was placed into the regenerated area, which was uncovered three months later to connect a screw-retained crown.<\/p>\n<p><strong>FOLLOW-UP<\/strong><\/p>\n<p>Three years postoperatively the soft tissue situation was stable without signs of mucositis at the implant site. The panoramic radiograph also revealed excellent osseointegration of the implant. No signs of bone loss at the implant were detectable.<\/p>\n<p><strong>CONCLUSION<\/strong><\/p>\n<p>The biomaterials combination of bovine bone mineral with hyaluronate and bone allograft provided optimal conditions for successful bone regeneration. cerabone\u00ae +HyA offers volumetric stability, while the allogeneic bone promotes fast natural bone regeneration. Moreover, thanks to its sticky properties after hydration, cerabone\u00ae +HyA makes defect augmentation effective and permits precise application of the granules, as well as quick defect contouring.<\/p>\n<\/div><\/div><\/div><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"","protected":false},"featured_media":24969,"template":"","meta":{"_acf_changed":false,"content-type":"","footnotes":""},"product_brand":[],"product_cat":[42],"product_tag":[238,32,107,135],"class_list":["post-24968","product","type-product","status-publish","has-post-thumbnail","product_cat-case-reports","product_tag-cerabone-hya","product_tag-jason-membrane","product_tag-maxgraft-granules","product_tag-ridge-reconstruction","first","instock","product-type-simple"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v27.7 (Yoast SEO v27.7) - https:\/\/yoast.com\/product\/yoast-seo-premium-wordpress\/ -->\n<title>First Clinical Case Report on Alveolar Ridge Augmentation 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