With the introduction of permamem®, botiss expands its regeneration system by offering an exceptionally thin, non-resorbable, biologically inert and biocompatible membrane made of 100% high-density polytetrafluoroethylene (PTFE).
permamem® maintains its structural integrity during implantation and over time. Due to its small pore size the membrane acts as an efficient barrier against bacterial and cellular penetration, and may therefore be left in place for open healing in certain clinical indications. permamem® can easily be removed after the desired healing time with a pair of tweezers.
After removal, the primary healing process and the reepithelialization of the regenerating soft tissue will be completed within one month.
permamem® fulfills the requirements of biocompatibility according to EN ISO 10993-1 and EN ISO 7405.
The biocompatibility of the membrane has been proven by in vivo preclinical data .
 Barbeck M. et al. unpublished