With the introduction of permamem^®, botiss expands its regeneration system by offering an exceptionally thin, non-resorbable, biologically inert, and biocompatible membrane made of high-density polytetrafluoroethylene (PTFE).

permamem^® maintains its structural characteristics both during the initial implantation and over the whole healing time. Due to its dense structure the membrane acts as an efficient barrier against bacterial and cellular penetration, and can therefore be used for open healing in certain indications.