Sidiropoulos, K., Roussou, K., Intzes, L., & Economides, N. (2019). Balkan Journal of Dental Medicine, 23(2), 102-107.
https://content.sciendo.com/abstract/journals/bjdm/23/2/article-p102.xml

This case report demonstrates the use of Guided Tissue Regeneration (GTR) for the treatment of a perio-endo lesion.

Methods:
Tooth 35 of a female patient was diagnosed with a pocket depth of 12 mm and grade two mobility. Radiographic analysis revealed an extended bone defect with involvement of the buccal plate and the presence of overextended filling material. Following root canal treatment, a periapical surgery using GTR was performed. After granulation tissue removal, cerabone® was applied, which was covered by a collagen membrane. The flap was closed and after one week, the sutures were removed.

Results:
An elimination of the periodontal pocket and a reduction of the mobility of the tooth was noted one year post-operative. Radiographic analysis revealed elimination of the periapical lesion. Two years post-surgery a reconstruction of the buccal plate was demonstrated by CBCT analysis. The patient remained asymptomatic over the whole observation period.

Conclusion:
The authors concluded that the endodontic-periodontal lesion could be efficiently treated by the described GTR procedure.