Root coverage using coronally advanced flap with porcine-derived acellular dermal matrix or subepithelial connective tissue graft: a randomized controlled clinical trial.

Tanaka Suzuki K, de Jesus Hernandez Martinez C, Irie Suemi M, Bazan Palito D, Reis Messora M, Scombatti de Souza SL, Belem Novaes Jr A, Chaves Furlaneto F A, Taba Jr M.

Investigation of a porcine-derived acellular dermal matrix (MD – mucoderm®) in root coverage procedures combined with extended coronally positioned flap (eCAF), in comparison to the subepithelial connective tissue graft (SCTG) associated with the eCAF in a split-mouth, double-masked, randomized controlled clinical trial.

Materials and methods:
Eighteen adult patients presenting bilateral type 1 gingival recession were randomly assigned to SCTG or MD groups. Clinical and patient-based outcomes (probing depth (PD), clinical attachment level (CAL), gingival recession height (RH), gingival recession width (GRW), keratinized tissue height (KTH), keratinized tissue thickness (KTT)) were recorded at 3 and 6 months after the surgical procedure.

A significant reduction in the mean recession height of 3.33 ± 0.89 mm to 1.24 ± 1.10 mm (mucoderm®) and 3.21 ± 0.8 mm to 0.83 ± 0.86 mm (SCTG) was found in both groups. Six patients in the mucoderm® group and eight in the control group obtained complete root coverage. The keratinized tissue height and thickness (KTT) showed a significant increase after 3 and 6 months in both groups. The average KTT gains were 0.39 ± 0.4 mm (mucoderm®) and 0.51 ± 0.5 mm (SCTG) (p < 0.05). Performing multivariate analysis suggests that mucoderm® addition to coronally advanced flaps may be similar to SCTG.
mucoderm® achieved similar results in comparison to SCTG. Regarding reduction of patient morbidity, mucoderm® can be used as an alternative grafting material for the treatment of gingival recessions.

Dr. Mario Taba

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