Zafiropoulos GG, Kačarević ZP, Qasim SSB, Trajkovski B. Medicina (Kaunas). 2020;56(5):E216.
https://pubmed.ncbi.nlm.nih.gov

The goal of the study was to evaluate the efficacy of permamem® for extraction socket management and alveolar ridge preservation.

Methods:
44 patients underwent tooth extractions and were assigned two treatment modalities. In group 1 socket preservation was performed, i.e. the extraction sites were grafted with cerabone® and covered with permamem®. In group 2, implants were placed in the alveoli and the periimplant gaps were grafted with cerabone®, which again was covered by permamem®. In both groups the membrane was partially left exposed to the oral cavity. Changes of vertical and horizontal ridge dimensions six months post-operative were analyzed using customize stents (T0 to T1).

Results:
– Uneventful healing for all patients, i.e. no reports of strong pain and no abscesses, exudates, swelling or allergic reactions
– No significant differences in alveolar bone loss from T0 to T1 between the two groups in the horizontal dimension for any tooth type
– Significant difference in alveolar bone loss from T0 to T1 between the two groups for only single-rooted maxillary premolars in the vertical dimension

Conclusion:
The described protocols for extraction socket management using permamem® in open healing consistently resulted in preservation of the alveolar bone following tooth extraction.

Prof. Gregor-Georg Zafiropoulos